Endocrine Abstracts

Background: Osteoprotegerin (OPG), a component of the RANKL/RANK/OPG pathway, can inhibit bone resorption by affecting osteoclastogenesis. Estrogens deficiency is associated with decreased expression of OPG and increased osteoclast activity, and thus can lead to disorders of bone remodeling.Objective: To analyze relationship between serum OPG and bone mineral density (BMD) in patients with Turner syndrome (TS) subjected to estroprogestagen (EP) treatment...

Introduction: Acne is the most commonly diagnosed skin condition in teenage girls and young women. Acne results from androgen excess or hypersensitivity of the skin to normal androgen levels. Therefore, determination of androgen concentrations in patients with acne may facilitate early implementation of appropriate treatment. The aim of the study was to retrospectively analyse the profiles of androgen concentration in female patients with acne of various severity.<p class=...